Product Name: CRK7 (380-388) pS383+pS385
Product Number: PE-04ALR99
| Size: | 200 µg | Price: | 68.00 | |
| 1 mg | $US | 136.00 | ||
| 5 mg | 297.00 |
Peptide Name: CRK7 (380-388) pS383+pS385
Product Use: Services as a blocking peptide for use with the CDK12-pS383+pS385 rabbit polyclonal antibody (Cat. No.: AB-PK566) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the first quarter of the protein. These are the major in vivo phosphorylation sites in CDK12. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RHS-pS-I-pS-PVR
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Product Use: Services as a blocking peptide for use with the CDK12-pS383+pS385 rabbit polyclonal antibody (Cat. No.: AB-PK566) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the first quarter of the protein. These are the major in vivo phosphorylation sites in CDK12. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RHS-pS-I-pS-PVR
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1372.35 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: CRK7 - pS383+pS385 phosphosite-specific antibody (Cat. No.: AB-PK566)
Peptide Molecular Mass Calculated: 1372.35 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: CRK7 - pS383+pS385 phosphosite-specific antibody (Cat. No.: AB-PK566)
Scientific Background: CDK12 (CRK7) is a protein-serine/threonine kinase of the CMGC group and CDK family. Insertional mutagenesis studies in mice support a role for this protein kinase in mouse cancer oncogenesis.
© Kinexus Bioinformatics Corporation 2017