Product Name: EphB4 (593-599) pY596
Product Number: PE-04AMB95
Size: 200 µg      Price:47.00
1 mg      $US94.00
5 mg      206.00
Peptide Name: EphB4 (593-599) pY596

Product Use: Services as a blocking peptide for use with the EphB4-pY596 rabbit polyclonal antibody (Cat. No.: AB-PK612) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the EphA2_TM region between the transmembrane and kinase catalytic domains. This is the major in vivo phosphorylation sites for EphB3. The effect of its phosphorylation is unclear.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: PFT-pY-EDP

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys

Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1121.1 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: EphB4 - pY596 phosphosite-specific antibody (Cat. No.: AB-PK612)

Scientific Background: EphB4 is a receptor protein-tyrosine kinase of the TK group and Eph family. It is a receptor kinase that will bind the ephrin-B family of ligands (ephrin-A1, B2, or B3) on adjacent cells to mediate cell-contact signalling. EFNB2 binding to EphB4 can be inhibited with a L95R mutation.