Product Name: Fused (156-162) pS159
Product Number: PE-04AMO99
| Size: | 200 µg | Price: | 42.00 | |
| 1 mg | $US | 84.00 | ||
| 5 mg | 185.00 |
Peptide Name: Fused (156-162) pS159
Product Use: Services as a blocking peptide for use with the Fused-pS159 rabbit polyclonal antibody (Cat. No.: AB-PK643) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. S159 phosphorylation is predicted to be stimulatory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: VLT-pS-IKG
Peptide Modifications N Terminus: Free amino
Product Use: Services as a blocking peptide for use with the Fused-pS159 rabbit polyclonal antibody (Cat. No.: AB-PK643) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. S159 phosphorylation is predicted to be stimulatory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: VLT-pS-IKG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 970.1 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: Fused - pS159 phosphosite-specific antibody (Cat. No.: AB-PK643)
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 970.1 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: Fused - pS159 phosphosite-specific antibody (Cat. No.: AB-PK643)
Scientific Background: Fused (STK36) is a protein-serine/threonine kinase of the Other group and ULK family. It functions in the sonic hedgehog (Shh) signalling pathway. Fused regulates the activity of the transcription factors GLI1, GLI2, and GLI3 by opposing SUFU activity and stimulating nuclear translocation of the factors. Fused is also necessary for the assembly of the central pair apparatus in motile cilia. In addition, Fused activity is necessary for post-natal development, potential through its role in ciliary function or regulation of cerebral spinal fluid homeostasis.
© Kinexus Bioinformatics Corporation 2017