Product Name: KHS1 (171-177) pS174
Product Number: PE-04AND99
| Size: | 200 µg | Price: | 42.00 | |
| 1 mg | $US | 84.00 | ||
| 5 mg | 185.00 |
Peptide Name: KHS1 (171-177) pS174
Product Use: Services as a blocking peptide for use with the KHS1-pS174 rabbit polyclonal antibody (Cat. No.: AB-PK671) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. S174 phosphorylation is predicted to be stimulatory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: KRK-pS-FIG
Peptide Modifications N Terminus: Free amino
Product Use: Services as a blocking peptide for use with the KHS1-pS174 rabbit polyclonal antibody (Cat. No.: AB-PK671) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. S174 phosphorylation is predicted to be stimulatory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: KRK-pS-FIG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1088.22 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: KHS1 - pS174 phosphosite-specific antibody (Cat. No.: AB-PK671)
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1088.22 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: KHS1 - pS174 phosphosite-specific antibody (Cat. No.: AB-PK671)
Scientific Background: KHS1 (MAP4K5) is a protein-serine/threonine kinase of the STE group and STE20 family. It has been proposed to be upstream of the JUN N-terminal pathway and may respond to environmental stresses. A mutation in KHS1, K49R, inhibits the kinase phosphotransferase activity and inhibits downstream JNK proteins.
© Kinexus Bioinformatics Corporation 2017