Product Name: RIPK2 (173-179) pS176
Product Number: PE-04API75
Size:      $US
Peptide Name: RIPK2 (173-179) pS176

Product Use: Services as a blocking peptide for use with the RIPK2-pS176 rabbit polyclonal antibody (Cat. No.: AB-PK796) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. S176 phosphorylation stimulates phosphotransferase activity.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: MSL-pS-QSR

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1061.14 Da

Storage Conditions: -20°C

Related Product 1: RIPK2 - pS176 phosphosite-specific antibody (Cat. No.: AB-PK796)

Scientific Background: RIPK2 (CARD3) is a protein-serine/threonine kinase of the TKL group and RIPK family. It plays an essential role in modulation of innate and adaptive immune responses. It Is activated by phosphorylation at S176.